In adult patients with diabetes not adequately controlled on mealtime insulin
SYMLIN® (pramlintide acetate) injection may cause serious side effects, including:
The most common side effects of SYMLIN include:
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of SYMLIN. For more information, ask your healthcare provider or pharmacist.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
SEVERE HYPOGLYCEMIA: SYMLIN can cause serious side effects, including severe low blood sugar (hypoglycemia). Even when SYMLIN is carefully added to mealtime insulin therapy, your blood sugar may drop too low, especially if you have type 1 diabetes. If this severe low blood sugar happens, it is seen within 3 hours after a SYMLIN injection. Symptoms of severe low blood sugar and low blood sugar include:
People who have severely low blood sugar have had injuries while driving their car, operating heavy machinery, or doing other dangerous activities. You and your healthcare provider should talk about a plan to treat low blood sugar. You should have fast-acting sugar (such as hard candy, glucose tablets, juice) or glucagon for injection with you at all times. Call your healthcare provider if you have severe low blood sugar or if you have low blood sugar more often than normal.
SYMLIN can cause low blood sugar (hypoglycemia). When starting SYMLIN, you will need to reduce your dose of mealtime insulin. Your healthcare provider will tell you how to reduce your dose of mealtime insulin the right way.
You must check your blood sugar as often as your healthcare provider tells you to, which may include before and after every meal and at bedtime. Your healthcare provider may make changes to your insulin dose to better control your blood sugar. Your healthcare provider should tell you what the right dose of insulin is for you.
Never mix SYMLIN and insulin. Insulin can affect SYMLIN when they are mixed together.
You have a higher chance of getting severe low blood sugar if you:
SYMLIN slows stomach emptying and can affect medicines that need to pass through the stomach quickly. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
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There are many strategies for eating healthy with diabetes.
Get a list of questions to ask your healthcare provider and see if adding SYMLIN is an option for you.